Thursday, September 29, 2011

Nature and Limits of Science

Science is a public domain and is free from any social or political situation.
The scientific advances made by a country have global impact. For instance: polio vaccine. Scientific research also helps in the betterment of one country through research project grants that can be granted to the needy from various research institutions across the globe. For example, BCPB (British Counsel for Prevention of Blindness) has granted a Trachoma Research Funding Project to Tumaini University, Tanzania, Africa .Also along with the advantages, it has certain limitations as well. All research is funded, and any situation that affects a country’s financial situation as a whole will have its effect on research. Scientific findings are reported back to the community and will be subject to discussion, which may also result in a change in research policies.

Friday, September 23, 2011

GLOBAL WARMING: Fact or Myth?

 
INTRODUCTION:

In the year 2009, more than 200 countries participated in a climate control conference held in Copenhagen for discussing the threats posed to the environment by global warming. The representatives of the countries along with more than 2,500 scientists from several countries were of the opinion that global warming is a major threat to the environment and the future of human population because of pollution and greenhouse gases in particular. Despite of that many scientists were debating that whether this climate change was caused due to human activities or the natural process in the universe and is affecting earth’s climate. There are several natural factors that determine earth’s environment, such as the orbit and degree of tilt determine the warming and cooling of earth. Moreover volcanic eruptions were a cause of global warming in the prehistoric era but due to reduction in these eruptions lately life forms produced on earth. The fact cannot be ignored that after the industrial revolution, the warming of the earth has increased by 35% due to greenhouse gas emission (Edwards 2010).
Greenhouse gases are those gases which trap the heat in the atmosphere and emit radiation which affects the temperature of the surroundings. Greenhouse gases involves several gases produced naturally or by human activities such as carbon dioxide (CO2), Methane (CH4), Nitrous oxide (N2O), and other fluorinated gases etc (USEPA 2011).   Although scientists believe that natural process have also caused a variable change in earth’s atmosphere but it has been caused mainly due to human activities emitting greenhouse gases, deforestation, emission of aerosols etc (Mohr 2005 & Mitchell 2010).
The scientists had predicted about the changes in temperature in the coming decade as the atmosphere of earth is continuously changing naturally but studies showed that the climate and temperature of the earth has increases at a much higher rate than the scientists predicted and is still accelerating which can have disastrous consequences such as floods, extreme weather and mass extinction of species, skin diseases and other epidemics etc. (Meinshausen et al, 2009).  
Human activities have emitted a lot of carbon dioxide in the earth’s atmosphere. A study showed that the natural carbon sinks of the nature, where carbon was absorbed and diminished, have been disrupted by human activities. According to a report by US National Oceanic and Atmospheric Administration (NOAA), the concentration of carbon dioxide alone in the environment has elevated up to 19 billion tones since past four years. And after carbon dioxide, it is methane whose concentration has been increased considerable in the past few years (Greenhouse Gas, 2011).

The graph below shows an increment in the amount and concentration of greenhouse gases such as methane, carbon dioxide, nitrous oxide etc. over a decade.

MAJOR THREATS POSED BY GLOBAL WARMING:
Even a small rise in the global temperature can give rise to extreme situations because the entire environment is interconnected with each other. Several factors such as, water currents, rainfall, wind, intensity of sunlight, atmospheric pressure, presence of debris in the atmosphere etc  are connected with each other and together form the weather of the earth. If any of these factors in misbalanced it can pose major threats to environment. According to various researches and studies it has been concluded that if the atmospheric temperature increases, it can lead to increase in the sea level by 0.09 - 0.88 m (Stanford Solar Center 2008) because of the melting of glaciers and polar ice caps, increase in storms, floods, drought and other such abrupt changes in the climate and if it is nor brought under control, then by the end of this century we can expect to see a raise of 7 °F in earth’s climate. Global warming is a serious threat posed to the earth’s environment and can have severe effects which can ultimately lead to the extinction of several wildlife and other species including human being from the face of earth (Edwards, 2010). It also poses a major threat to human health because it can result in the spreading of diseases such as malaria and other epidemic due to poor air quality and living conditions. Greenhouse gases are also a major cause of atmospheric pollution causing breathing problems and asthma. The depletion of ozone layer can allow the UV lights to enter into earth’s atmosphere and can give rise to visual and skin related diseases such as skin cancer. There have been several cases of skin cancer reported in the United States due to radiation of the sun   (Stanford Solar Center 2008).
CONTRIBUTION OF GREENHOUSE GASES IN GLOBAL WARMING:
Greenhouse gases play a major role in global warming. Green house gases such as methane, nitrous oxide and chlorofluorocarbons even if found in low concentrations, can give rise to major issues because even though they are lower in concentration but their each molecule can absorb high amount of infrared radiation as compared to molecules of other gases. According to a study, it was observed that greenhouse gases have caused about 43% of elevation in radiative forces and therefore pose a major threat to environment. (Lashof & Ahuja, 1990)
We know that our atmosphere is made up of 78% nitrogen and 21% oxygen along with water vapor and several other gases contributing the rest. These other gases which include argon, carbon dioxide, neon, helium, methane, hydrogen, nitrous oxide and ozone are the cause of global warming and greenhouse gas issues.  Natural and various human activities lead to the emission of greenhouse gases (carbon dioxide, methane, nitrous oxide and fluorinated gases which includes fluorine, chlorine and bromine). These gases trap the atmospheric heat and emit radiation and their increased concentration in the atmosphere which can lead to global warming. (Greenhouse Gas, 2011)   
Why are they called “greenhouse” and how do they cause global warming:
The earth absorbs the heat in the daytime and radiated it in the space during the night except some amount which is used to maintain earth’s atmosphere. These specific gases do not allow the earth to radiate the heat back in the space and trap it in the earth’s atmosphere making the atmosphere of the earth warmer than required and converting the earth into something which can be compared to a green house. That is why these gases are called ‘greenhouse gases”.  (Greenhouse Gas, 2011)
The emission of greenhouse gases has resulted into a variable depletion of ozone layer found in the atmosphere which protects the atmosphere from harmful ultraviolet radiation. With the depletion of atmospheric ozone, the UV rays can easily penetrate into earth's atmosphere causing elevation in earth's atmosphere. The green house gases are one of the primary reasons for ozone depletion because when they move above to the stratosphere, they do not get washed away by rainfall but instead they react with atmospheric ozone and react with it to destroy it. The scientists have estimated that with a decrease on one percent atmospheric ozone, there will be an increase of about two percent in the penetration of UV light in the earth’s atmosphere. (Greenhouse Gas, 2011)
Although, certain scientists debate that these changes in earth’s atmosphere are not caused by human activities, but are seen due to natural changes such as cloud cover. They also suggest that increased level of carbon dioxide and other greenhouse gases are the result of warming of earth, changes in the solar system and radiation of the sun and human activities are not the potential cause of global warming because earth’s atmosphere is continuously changing over the years (Edwards, 2010).
CONCLUSION:
There are certain reports by the workers who claim the temperature of the earth is not increasing but dropping eventually, the increase in the level of carbon dioxide is due to natural changes in earth’s environment, activity of the sun and global warming is a myth. But the reports from Intergovernmental Panel on Climate Change (IPCC) support the fact that global warming is a result of human activities which produce factors such as greenhouse gases, aerosols, debris etc. which continue to deplete the earth’s covering and this theory is the result of a research conducted on the CO2 trapped in the ice. Although there is not much reports of the opinion that global warming is not driven by human activities and most of the studies support the human driven theory of climate change. It is evident that human activities have increased the level of atmospheric pollution and given rise to environmental problems such as deforestation, pollution of water reservoirs such as rivers and increase in the carbon dioxide level by burning of fossil fuels etc. In the end, no matter what factors are responsible for global warming, it is our duty to keep our planet pollution free and reduce the emission of harmful gases and byproducts which whether or not harm the environment, do harm human health.

Saturday, September 10, 2011

Model of E.coli replication fork

A replication fork is formed during the replication of the DNA and is initiated by the enzyme helicase which breaks the hydrogen bond formed between the nucleotides thus separating the strands. The two strands will act as a template for leading and lagging strand, during replication. In the leading strand, replication is carried out in 3’ to 5’ direction allowing the new strand to be synthesized 5’ to 3’. The DNA polymerase continuously reads and adds nucleotides to the growing strand. In the lagging strand, the replication fork moves in 5’ to 3’ direction and the growing strand is synthesized 3’ to 5’. Since DNA polymerase catalyzes the polymerization of dNTPs only in the 5′ to 3′ direction, therefore the enzyme primase reads the DNA and adds short segments of RNA to it. DNA polymerase lengthens the segments and Okazaki fragments are formed which are joined by DNA ligase. Thus with the help of leading and lagging strand the replication form moves forward till the total DNA is replicated.